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In general accurate results for
2020-12-29
In general, accurate results for the prediction of the solubility in scCO2 + cosolvents using the CPA-EoS were verified. ALD values for each solute (Table 1) varied from 0.04 to 1.5. Few solutes, such as lauric acid, myristic acid, hydroquinone and salicylic acid, presented the highest ALD values. A
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POE specialises Rogers definition of engineering to systems
2020-12-29
POE specialises Rogers' definition of engineering [37] to systems engineering as: As such, systems engineering becomes a problem solving exercise, the problem being, given a physical environment E, to find the system S that Cholic acid meets a real-world need N to the satisfaction of a group of st
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Moreover as shown in Fig f while the knockdown
2020-12-28
Moreover, as shown in Fig. 5f, while the knockdown of SMURF2 in wild-type SKF38393 HCl has no significant effect on HSP27, in CK2α/α′(−/−) cells it leads to an increase of HSP27 level. These results suggest that SMURF2 affects HSP27 protein stability only when overexpressed, at least in our cell mo
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Because of the lack of sequence current
2020-12-28
Because of the lack of sequence, current knowledge on the cellular regulation of CoA-IT is scarce. However, recent work has suggested an interesting new role for CoA-IT in regulating the extent of the AA mobilization response in primed macrophages. Bacterial lipopolysaccharide (LPS) is a poor trigge
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In sum although it is reasonable to assume that the
2020-12-28
In sum, although it is reasonable to assume that the activities of an enzyme on alternative (metabolically available) substrates may often depend on neutral drift, the point is difficult to prove because various types of selective pressures can be at play, and these will be different in different or
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Since the dideoxy analogues and
2020-12-28
Since the 1,2-dideoxy analogues, and , served as substrates for TgTCEA and TgTCEB, respectively, with the higher affinity (lower ) and lower turnover number (lower ) than their authentic substrates, PosA and PosB (such trend was more evident on analogue for TgTCEB than on analog for TgTCEA), an i
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Pleuromutilin mg Studies using SERPINB deficient mice establ
2020-12-28
Studies using SERPINB1-deficient mice established the significant role for SERPINB1 in protecting lung antimicrobial proteins from proteolysis during microbe infection and its regulatory role in sustaining the balance of neutrophil reserve [15]. Neutrophil serine proteases (NSPs) (elastase, cathepsi
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Index Kit 2 Ginsenoside Re lysine mixture had increased anti
2020-12-28
Ginsenoside Re-lysine mixture had increased anticancer effects upon heat processing by regulating Bcl-2 and Bax (Yamabe et al., 2013). Ginsenoside Re (20mg/kg) inhibited NF-κB activation by inhibiting LPS binding to TLR4 on macrophages in TNBS-treated mice (Lee, Hyam, Jang, Han, & Kim, 2012). The ch
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The murine subfamily members including and
2020-12-28
The murine subfamily members including , , , and have been identified and their encoded proteins showed deubiquitinating enzymatic activity , , , . It has been demonstrated that is an immediate-early gene induced by IL-3 in B-lymphocytes and is an IL-2 specific immediate-early gene in T-lymphoc
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br Are incretins the only mediators of the anti
2020-12-28
Are incretins the only mediators of the anti-hyperglycaemic effects of DPP-4 inhibitors? Even though both GLP-1 and GIP were identified as substrates for DPP-4 early on [17], [19], [20], [22], and DPP-4 inhibition in vivo raises levels of the intact endogenous forms of both of them [43], [44], fr
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Previous synthetic lethal screening efforts Cox et
2020-12-28
Previous synthetic lethal screening efforts (Cox et al., 2014) have mainly used RNAi as a means of identifying potential targets (Barbie et al., 2009, Kim et al., 2016, Luo et al., 2009, Scholl et al., 2009), although a few screens (Shaw et al., 2011, Steckel et al., 2012) have been performed with s
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Recent studies have shown arsenic could cause
2020-12-28
Recent studies have shown arsenic could cause autophagic cell death in malignant cells, including leukemia and malignant glioma NVP-BKM120 [16], [17]. However, at present, little is known about the consequences of arsenic-treated urothelial cells in autophagy and expression of its related proteins.
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Findings from the present study indicate
2020-12-28
Findings from the present study indicate that CRF1 receptors are especially important in fear acquisition. CP154,526 given before acquisition training, at least partly, reinstated the fear-potentiated startle response and blocked the development of contextual conditioned fear in SERT−/− rats. CP154,
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br Results On the th day the horizontal
2020-12-28
Results On the 8th day, the horizontal (Fig. 1) and vertical locomotor activity (Fig. 2) and the dorsal (Fig. 3) and lamotrigine striatal dopamine release (Fig. 4) increased significantly in nicotine-treated rats, compared with the saline-treated rats. Tukey post-hoc test revealed the following
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This review aims to examine the
2020-12-28
This review aims to examine the literature on chloride Tie2 kinase inhibitor synthesis in the context of transplacental transport. After a short overview of the general cellular functions of Cl− channels in epithelia and the molecular classifications of these channels, it will focus on the evidence
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