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br Discussion CML was the first malignancy to be
2019-04-28
Discussion CML was the first malignancy to be linked to a clear genetic abnormality, the Philadelphia chromosome. This chromosomal abnormality is so named because of the city in which it was first discovered and described in 1960 by Peter Nowell and David Hungerford [1]. The fusion protein result
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br Discussion Prehabilitation is a program to enhance functi
2019-04-26
Discussion “Prehabilitation” is a program to enhance functional capacity and psychological health to enable patients to withstand an upcoming stressor, e.g. surgery. It is intended to reduce treatment-related morbidity and/or mortality, to decrease length of hospital stay and/or re-admission, and
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hmg-coa reductase inhibitor The appearance of J wave or ER i
2019-04-26
The appearance of J wave or ER is now recognized to predispose to the development of arrhythmogenesis when associated with other cardiac disorders, such as ischemia, hmg-coa reductase inhibitor failure, and hypothermia. The J wave might predict prognosis of cardiac events in various heart diseases,
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El poeta becario no es la nica figura
2019-04-26
El poeta becario no es la única figura que impacta LY 2109761 esta generación; hay otra menos visible, pero que sin duda resulta también relevante para un campo como la poesía, de escaso interés comercial. En los espacios alternativos que no participan de la normativa burocrática, se crean figuras c
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In Jillian Pintye and colleagues from the Partners
2019-04-26
In Jillian Pintye and colleagues from the Partners PrEP study team present one of the largest and most comprehensive analyses of syphilis incidence in men and women and the effect of male circumcision. The investigators followed 4716 HIV-1 serodiscordant couples, of whom roughly 50% of the men were
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br Detection methods in implantable monitoring device State
2019-04-26
Detection methods in implantable monitoring device State-of-the-art, implantable, dual-chamber cardiac devices provide useful diagnostic information, including the numbers and duration of automatic mode switch (AMS) episodes upon detection of AT/AF. However, to collect accurate diagnostic informa
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Aside from distinct technical approaches used the
2019-04-26
Aside from distinct technical approaches used, the well-established RANKL and RANK expression patterns in the bone further substantiates the expression patterns defined in the current study of OS. RANKL and RANK play major roles in bone metabolism due to the critical role of this pathway in osteocla
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EBV occasionally reactivates to switch its replication mode
2019-04-25
EBV occasionally reactivates to switch its replication mode from latent to lytic, producing a large number of infectious virions with the lysis of host cells [7]. Although reactivation is dangerous for the virus, its triggering factors have not yet been identified. EBV reactivation is associated no
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br Conventional mapping and ablation of ventricular
2019-04-25
Conventional mapping and ablation of ventricular tachycardia Substrate mapping during sinus rhythm Technical issues Conclusion Conflict of interest Introduction By eliminating the arrhythmogenic focus, catheter ablation can be a curative therapy of ventricular tachyarrhythmias (VTA
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br Materials and methods br Results br Discussion
2019-04-25
Materials and methods Results Discussion This retrospective analysis examined data from patients with early breast cancer treated over a 12-year period (1997–2009) in a real-world setting. The proportion of patients receiving adjuvant BP therapy dramatically increased during the study perio
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br In Sanguinetti et al
2019-04-25
In 1996, Sanguinetti et al. and Barhanin et al. independently found that, when coassembled with the accessory subunit KCNE1, the KCNQ1 and KCNE1 complex could form a channel that very closely exhibited conductive and kinetic properties similar to that of cardiac IKs[14,56]. Kass and coworkers subs
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br Conclusion The mm Jamshidi is feasible practical and
2019-04-24
Conclusion The 2mm Jamshidi is feasible, practical, and yields an adequate sample to assess bone structure and quality using microCT and histomorphometry in breast cancer patients. Additional samples are required to assess reproducibility, effect of bisphosphonates on bone quality and novel infor
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trpv1 antagonist Amongst other anti arrhythmic medications d
2019-04-24
Amongst other anti-arrhythmic medications, disopyramide (class 1A AAM) has anticholinergic side effects such as dry mouth, urinary hesitancy, constipation and exacerbation of conditions like glaucoma and myasthenia gravis. Disopyramide acts by targeting the fast sodium trpv1 antagonist in the cardi
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Despite our best efforts the
2019-04-24
Despite our best efforts, the cause of SCD in young individuals is sometimes not established; no cause is identified in up to 40% of cases. Importantly, whether a cause of death is established or not, the possibility of an underlying inherited cardiac disorder remains in many cases, including the po
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Estos cuatro momentos expresan los
2019-04-24
Estos cuatro momentos expresan los pasos más importantes del desprendimiento de la crítica y la práctica literaria en relación con la política partidista. Es decir, son tomas de posición estético-literarias que abrigan en su interior tomas de posición política que, opioid receptor la postre, socavan
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