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farnesoid x receptor MADIT trial enrolled adult patients wit
2019-06-11
MADIT trial enrolled 196 adult patients with prior myocardial infarction more than 3 weeks (Q wave or elevated cardiac enzyme), with non-sustained ventricular tachycardia (a run of 3–30 of ventricular ectopic beats with a rate more than 120 beats per minute), with left ventricular ejection fraction
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MCL has a poor long term response
2019-06-11
MCL has a poor long-term response to current treatment strategies, for the most commonly used R-CHOP chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone), the remission rate is good (75–96%) but brief in duration. Despite the study of several other chemotherapy regimens
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Dexamethasone with its anti inflammatory properties
2019-06-11
Dexamethasone, with its anti-inflammatory properties, has been shown to be an effective medication in the treatment of pain flare and is hypothesized to prevent the phenomenon as well [12]. Despite a lack of literature investigating this hypothesis, currently published phase I and II trials have pro
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rna helicase br Case report A year old woman who had been
2019-06-11
Case report A 41-year-old woman who had been fitted with a pacemaker for bradycardia 18 years prior presented for lead extraction on account of device infection. She had a left pectoral dual chamber pacemaker, with two tined leads: an atrial lead of 5524 M (Medtronic, Dublin, Ireland) and a ventr
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The Cl HCO anion exchanger
2019-06-11
The Cl−/HCO3− anion exchanger 2 (AE2) is found on cholangiocytes and regulates intracellular pH homeostasis and stimulates bicarbonate secretion. Previous reports have revealed that PBC patients show decreased biliary AE2 expression, and researchers hypothesized that this decrease in AE2 adenosine k
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We would like to also clarify that we do
2019-06-11
We would like to also clarify that we do not underestimate the CIs in our study through the assumption that GDP was observed independently for every child in the survey. The multilevel design and clustering of standard errors at the survey level accounts for the fact that GDP is not observed indepen
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atp citrate lyase inhibitor La relaci n entre el narcotr
2019-06-11
La relación entre el narcotráfico y los grupos guerrilleros y los paramilitares se ha dado: “[…] no sólo como fuente de financiación sino como actor con intereses propios, ya que han aumentado significativamente las ‘familias’ que se dedican al tráfico de drogas, que a su vez están aumentando sus fo
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In the days before Christmas adverse
2019-06-11
In the days before Christmas, 1952, adverse weather conditions and the burning of sulphurous coal led to the death of almost 12 000 people in London. Despite improvements in pollution prevention since the “Great Smog”, London continues to experience toxic air pollution linked to thousands of prematu
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gap26 br Procedural endpoints The most commonly employed ele
2019-06-11
Procedural endpoints The most commonly employed electrophysiological endpoint is the achievement of noninducibility. While noninducibility has been shown to be predictive for clinical freedom from recurrent VT, it has not been uniformly the case [1,2]. Inducibility of VT is probabilistic and rare
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order AN-2728 Roux en Y gastric bypass surgery is a
2019-06-11
Roux-en-Y gastric bypass surgery is a common cause of malabsorption associated with hyperoxaluria in obese patients and those with malignancies. Postoperatively, patients may have steatorrhea, weight loss, and diarrhea, resulting in malabsorption syndrome, which would increase excessive intraluminal
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br Introduction Patients with advanced breast
2019-06-11
Introduction Patients with advanced breast, prostate, lung and colo-rectal cancer frequently develop bone metastases (BMs). These lesions may be asymptomatic or may cause pain, pathologic fractures, malignant hypercalcemia, epidural spinal cord compression and/or shorten survival [1]. The underly
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In contrast to the low insertion frequency in
2019-06-10
In monoamine transporter to the low insertion frequency in Asian population for HERV-K113 (13%) and -K115 (4%) [10], we demonstrate herein high insertion frequency (89.3%) of HERV-H in the Singapore population, and observe interesting correlation between prevalence and age-standardized incidence ra
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By showing the great variability in surgical outcomes across
2019-06-10
By showing the great variability in surgical outcomes across LMICs, Uribe-Leitz and colleagues have shared with the world instructive knowledge that aids our ongoing advocacy efforts to promote quality in surgical care in resource-limited settings. Ultimately, for destitute sick and injured patients
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br Epidemiology Electrophysiological BrS phenotypes occur pr
2019-06-10
Epidemiology Electrophysiological BrS phenotypes occur predominantly in young male adults (GSK1324726A manufacturer rate, autonomic nervous system activity, some types of drugs, and a febrile state. Therefore, the true prevalence of BrS in the general population is difficult to estimate. However
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br Conclusion Conduction disorders were localized and
2019-06-10
Conclusion Conduction disorders were localized and inhomogeneous in patients with ischemic heart disease, in whom CRT efficacy was slightly low; therefore, detailed optimization using echocardiography, radioisotopes, Swan–Ganz catheterization, and other methods should be carefully performed as ne
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