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br Other drugs Overdose of diphenhydramine
2019-05-08
Other drugs Overdose of diphenhydramine (an H1 histamine receptor antagonist) is reported to induce a BrS phenotype [58,59]. Antihistamines are known to cause QT prolongation secondary to IKr inhibition. Cocaine is known to block the sodium tak1 kinase and thus to unmask a BrS phenotype [60]. Al
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Chronic myelomonocytic leukemia has been reported as
2019-05-08
Chronic myelomonocytic leukemia has been reported as the most prevalent concomitant hematological neoplasm, followed by myelodysplastic, myeloproliferative syndrome, and acute myeloid leukemia; on the other hand, Lymphoproliferative neoplasms were less frequency associated with SM-AHMND. In another
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br Case report A year old woman presented to our
2019-05-08
Case report A 58-year-old woman presented to our hospital with a history of several weeks of chronic dry cough and intermittent shortness of breath. On physical examination, the patient\'s blood pressure was 135/85 mmHg, oral temperature was 37.4 °C, pulse rate was 112/min, and her respiratory ra
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hcv protease inhibitors Seg n Patricia Fagen en su estudio
2019-05-07
Según Patricia Fagen, en su estudio clásico sobre el exilio español, “un numero sorprendente de jóvenes participaron en el Movimiento 1959 y muchos más hubieran participado si hubiesen creído que había algo significativo con lo que hubieran podido contribuir”. El espíritu de ruptura con las disputas
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I am delighted to introduce the inaugural issue of It
2019-05-07
I am delighted to introduce the inaugural issue of . It is very likely that you are reading this online, this being an online-only journal, although we have also printed this first issue in order to showcase the journal to readers of . What is certain is that, in accessing this article, and all the
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Evidence of the efficacy of topiramate in PTC
2019-05-07
Evidence of the efficacy of topiramate in PTC has been reported in the literature [41,42]. The largest study, an open-label trial by Celebisoy and colleagues [41], demonstrated the non-inferiority of topiramate to acetazolamide in the management of idiopathic intracranial buy NCT-501 in a populatio
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Findings children from households were enrolled either at ba
2019-05-07
Findings 5254 children from 3376 households were enrolled either at baseline or during the trial period. Mean 20-h kitchen concentration of PM2.5was reduced from 1386 μg/m3 to 930 μg/m3 There was a strong secular decline in the incidence of ALRI over the period of the study. The intervention was ass
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br Conclusions Wavelet algorithm is
2019-05-07
Conclusions Wavelet algorithm is an effective tool for the discrimination of tachycardia. However, it is affected by myopotential interference, which can lead to inappropriate detections. Thus, we should keep this drawback in mind when results reveal a Can-RV coil EGM amplitude of less than 5mV.
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Introduction Metastasis to the bone is a common
2019-05-06
Introduction Metastasis to the bone is a common complication of breast, lung, prostate, gastrointestinal, haematological, melanoma, and other tumours [1–3]. In many patients with primary breast, prostate and lung primary tumours, bone metastases (BoM) are signs associated with the presence of disse
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In a recent study Nademanee et al reported additional eviden
2019-05-06
In a recent study, Nademanee et al. [76]. reported additional evidence pointing to pathologic changes in the RVOT of patients with BrS that have proved undetectable by echocardiography or MRI. In contrast, imaging techniques in ARVC clearly display morphologic and functional changes (e.g., dilation
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br Case report A year old
2019-05-06
Case report A 38-year-old patient with pectus excavatum received a dual chamber ICD after resuscitated cardiac arrest due to ventricular fibrillation during myocardial infarction following vasculitis (Fig. 1, Panel A). He developed fever and chill after the ICD implantation, consistent with the g
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br Epigenetic regulation of genes involved in hepatic lipid
2019-05-06
Epigenetic regulation of genes involved in hepatic lipid metabolism by S1P and SHP The signaling cascade of CBA > S1PR2 > SphK2 > S1P > HDAC1/2 > increased hepatic gene expression can differentially up-regulate blocks of genes involved in the hepatic metabolism of sterols and lipids (Fig. 3, Tabl
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Sierra Leone Liberia and Guinea were among the
2019-05-06
Sierra Leone, Liberia, and Guinea were among the worst places to be a mother before the Ebola crisis. However, substantial progress had been made in recent years in terms of maternal mortality buy CCT251545 analogue and increased access to maternal and reproductive health care, resulting in 50% of
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To the best of our knowledge only one
2019-05-06
To the best of our knowledge, only one other group studied low-dose protracted oral clofarabine in MDS patients who failed hypomethylating agents. They studied 5mg (fixed dose) daily for 10 consecutive days of a 28-day cycle. All patients who were treated for 10 days had a greater than 25% drop in t
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br The L type calcium channel
2019-05-06
The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot
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