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br Role of the funding source br
2019-04-22
Role of the funding source Introduction Myeloproliferative neoplasms (MPNs) are stem-cell-derived disorders that cause overproduction of one or more of the formed elements of the blood. MPNs include chronic myelogenous leukemia (CML) and the Philadelphia-negative MPNs: polycythemia vera (PV),
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br Cholera remains a serious global public health
2019-04-22
Cholera remains a serious global public health problem, disproportionately affecting poor individuals, causing illness and death for thousands of people each year. Cholera cases are on the rise, with 47% more cases reported to WHO in 2014 than in 2013. Innovative approaches to control the disease
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En el encuentro con la prima
2019-04-22
En el encuentro con la prima, Isabel, los dos rivales conocen también (-)-p-Bromotetramisole Oxalate Clemencia, cuya presencia inicia una conversación entre los dos hombres. Es una escena esencial a la hora de examinar la relación de rivalidad entre ellos dos. Primero, discuten quién va a estar con
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In Philippe B scher and colleagues present the
2019-04-22
In , Philippe Büscher and colleagues present the first formal assessment under field conditions of the HAT Sero--SeT rapid diagnostic test and compared its diagnostic accuracy with two other current serological tests: CATT and immune trypanolysis (a very sensitive and specific test that requires lab
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br Acknowledgments This study was supported by a grant
2019-04-22
Acknowledgments This study was supported by a grant from the National Science Council (NSC 98-2314-B-075B-007-MY2). Introduction Many complications may occur following treatment of femoral shaft open fracture such as nonunion, malunion, delay union, bone defect, bone and joint deformity or st
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Bisphosphonates are the cornerstone of
2019-04-20
Bisphosphonates are the cornerstone of management in postmenopausal osteoporosis with randomised trial evidence of reductions in vertebral fractures for ibandronate [15] and both vertebral and non-vertebral fracture rates for alendronate [16], risedronate [17], and zoledronic polo like kinase [18].
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The presence of an inflammatory infiltrate is associated wit
2019-04-20
The presence of an inflammatory infiltrate is associated with poor prognosis in a number of malignancies, including those with a predilection for metastasis to bone. CAFs are capable of promoting, and maintaining an inflammatory environment by recruiting immune cells; in particular monocyte/macropha
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br In Gretchen Stevens and colleagues update of
2019-04-20
In Gretchen Stevens and colleagues\' update of global, regional, and national trends in haemoglobin concentration and levels of anaemia emphasises both the massive extent of the problem, and its very slow rate of improvement. About 30% or more of women and children younger than 5 years are affect
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The approach used of estimating effectiveness relative to a
2019-04-20
The approach used, of estimating effectiveness relative to a matched counterfactual, can be regarded as an attempt to reach the ideal estimation of relative risk, namely the comparison of a population to itself with the exposure removed. However, it is not possible to know exactly what would have ha
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Efforts to estimate the global burden of
2019-04-20
Efforts to estimate the global burden of typhoid fever can be traced to a meeting of the Pan American Health Organization in 1984 and publication of the outcome in 1986. Although an important first step, the 1984 study was recognised as having a number of limitations including provision of scanty me
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br After several decades of community based interventions an
2019-04-20
After several decades of community-based interventions and surveillance, on Nov 15, 2016, Morocco was recognised by WHO as having eliminated trachoma as a public health problem. A formal ceremony, involving the handover of a letter of recognition from Margaret Chan, WHO\'s Director-General, marked
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In our opinion environmental pollution should
2019-04-19
In our opinion, environmental pollution should be considered as a common risk factor for both dementia and schizophrenia. Studies are warranted to test this hypothesis, and if confirmed, the clinical implications could be of great importance for public and mental health. Future research, including l
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br Discussion Rarely a breast cancer patient has histologica
2019-04-19
Discussion Rarely, a breast cancer patient has histologically proven breast cancer found outside the breast without a detectable primary breast tumor. Almost always the site of detected disease is an axillary lymph node. The incidence of axillary breast cancer with occult primary is relative low,
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In the present study we found
2019-04-19
In the present study, we found that stathmin was significantly down-regulated upon treatment with a combination of Zol and gefitinib. The down-regulation of stathmin, which was not detected by 2-D DIGE after treatment with either agent alone, was considered to be attributable to cooperative effect o
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The main inherited arrhythmogenic causes of
2019-04-19
The main inherited arrhythmogenic causes of SCD in the young are summarized in Fig. 1. These arrhythmogenic disorders include familial long QT syndrome (LQTS), catecholaminergic polymorphic ventricular tachycardia (CPVT), Brugada syndrome (BrS), idiopathic ventricular fibrillation, early repolarizat
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